{"product_id":"pure-encapsulations-calm-mind-600-capsules","title":"Pure Encapsulations Calm Mind 60 Capsules","description":"\u003cdiv class=\"accordion-header\" role=\"button\" aria-expanded=\"true\" id=\"accordion-header-0\" aria-controls=\"accordion-panel-0\" tabindex=\"0\"\u003e\n\u003cp\u003e\u003cstrong\u003eBenefits \u0026amp; Features\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"accordion-panel open\" id=\"accordion-panel-0\" role=\"region\" aria-labelledby=\"accordion-header-0\" aria-hidden=\"false\"\u003e\n\u003cdiv class=\"accordion-attribute accordion-attribute-benefits-features\"\u003e\n\u003cul\u003e\n\u003cli\u003eSupports emotional well-being\u003c\/li\u003e\n\u003cli\u003eSupports a positive mood and emotional outlook\u003c\/li\u003e\n\u003cli\u003ePromotes a calm state of mind\u003c\/li\u003e\n\u003cli\u003eSupports sleep with continued use\u003c\/li\u003e\n\u003cli\u003eClinically studied saffron (affron\u003cspan style=\"font-size: 0.875rem;\"\u003e)\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003eClinically studied curcumin (Theracurmin\u003cspan style=\"font-size: 0.875rem;\"\u003e) with 27x enhanced bioavailability\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"font-size: 0.875rem;\"\u003e\u003cspan\u003eCalm Mind combines two clinically studied botanical extracts, saffron (affron\u003c\/span\u003e\u003cspan\u003e) and curcumin (Theracurmin\u003c\/span\u003e\u003cspan\u003e), to support a positive mood, a calm state of mind and emotional well being. In a double-blind trial involving 128 adults self-reporting low mood, saffron (affron\u003c\/span\u003e\u003cspan\u003e, 28 mg\/day) resulted in a significant decrease in negative mood and symptoms related to stress after 4 weeks compared to placebo.\u003c\/span\u003e\u003cspan\u003e Other studies indicate that saffron also supports sleep with continued use.\u003c\/span\u003e\u003cspan\u003e The regulation of mood and emotional state is influenced by the immune system, and emerging research points to an impactful role of immune mediators known as cytokines.\u003c\/span\u003e\u003cspan\u003e Lower plasma levels of certain cytokines, such as IL-6 and TNF-α, are associated with positive mood and emotional well-being.\u003c\/span\u003e\u003cspan\u003e In preclinical models, curcumin moderates the production of the cytokines IL-1β, IL-6, and TNF-α\u003c\/span\u003e\u003cspan\u003e and moderates pro-inflammatory cytokine pathways in the brain.\u003c\/span\u003e\u003cspan\u003e However, the low oral bioavailability of curcumin may limit its ability to support brain function. Theracurmin\u003c\/span\u003e\u003cspan\u003e is 27 times more bioavailable than standard curcumin.\u003c\/span\u003e\u003cspan\u003e In a study of 40 adults (51–84 years of age) Theracurmin\u003c\/span\u003e\u003cspan\u003e containing 90 mg curcumin twice daily for 18 months significantly improved short-term, verbal and visual memory and attention.\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"Pure Encapsulations","offers":[{"title":"Default Title","offer_id":46826720755878,"sku":"WSPEN0605","price":70.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0675\/9628\/8166\/files\/WS-Pure-Encapsulations-Calm-Mind-60-Capsules.webp?v=1776360411","url":"https:\/\/www.wellnessupplement.com\/products\/pure-encapsulations-calm-mind-600-capsules","provider":"Wellness Supplement","version":"1.0","type":"link"}