HistaGest-DAO provides supplemental diamine oxidase (DAO), the enzyme responsible for breaking down food-derived histamine, to help support normal and healthy histamine metabolism.* Histamine is a bioactive compound produced in the body in response to an injury or the presence of foreign substances and is present in all foods in the diet in various degrees. Some foods are known to be high in histamines, such as fermented foods and alcoholic beverages. Lower DAO activity may result in higher levels of histamine being absorbed through the small intestine and accumulating in the blood.

Each tablet provides 20,000 histamine-degrading units (HDU) of diamine oxidase (DAO) from porcine kidney extract to promote the degradation of dietary histamines. HistaGest-DAO is formulated with gastro-resistant, coated tablets with delayed-release technology that allows the DAO enzyme to reach the small intestine where it performs its action. Taking one tablet before each meal promotes the amount of DAO in the small bowel to help break down histamine in the digestive tract and soothe digestive discomfort associated with sensitivity to histamine-rich foods.

Read Less

Take 1 tablet just prior to the consumption of histamine-rich foods or as directed by your health-care practitioner. (Take by mouth and swallow whole 20 minutes before meals.)

Read Less

††An IPSOS 2023 survey among US functional medicine practitioners, in an average month, Designs for Health is their personally most trusted practitioner supplement brand, meaning a brand that is sold by healthcare practitioners in their office.

††An Ipsos 2023 study among a random sample of 160 functional medicine practitioners including Doctor's of Osteopathic Medicine, Pharmacists, Acupuncturists, Athletic Trainers, Personal Trainers, Fitness Trainer/Coaches, Chiropractors, Integrative Medicine Specialists, Naturopathic Doctor, Homeopaths, Medical Doctors, Physical Therapists, Nurse Practitioner/Physician Assistants, Registered Nurses, Nutritionists, Massage Therapists, Occupational Therapists and Dieticians that are aware of Designs for Health and recommend supplements to their patients.

At Wellness Supplement, we strive to provide up-to-date product information and images on our website. However, please be aware that manufacturing changes to packaging or ingredients may occasionally occur before updates are reflected on our site.

Products may ship with different packaging due to recent updates from the manufacturer or supplier. In most cases, the ingredients remain the same despite the packaging change. However, we strongly recommend reading all labels, warnings, and directions before use. Please do not rely solely on the information provided on Wellness Supplement’s website.

Probiotics are shipped with a free ice pack. While the product may not be cold upon delivery, the ice pack helps maintain a cooler temperature during transit. Please consider weekend and holiday delays when placing an order. 

Read Less