HMF Baby Drops probiotic provides a clinically studied combination of two strains, Bifidobacterium longum subsp. longum (KABP-042) and Pediococcus pentosaceus (KABP-041), which help colic symptoms relief in infants such as crying, fussing or irritability. Infant colic, or excessive crying syndrome is a behavioural syndrome in 1- to 5-month-old infants characterized by long periods of crying and hard-to-soothe behaviour. Infant colic is classified as a Functional Gastrointestinal Disease (FGID) and comprises one of the most common causes of visits to paediatricians during the first 3-4 months of an infant’s life. Research has found the gut bacteria of colicky infants to be less diverse than infants, and it has been suggested that the difference in gut microflora plays an important role in the pathogenesis of colic. According to a recent clinical trial, infants given the probiotic combination, Bifidobacterium longum subsp. longum (KABP-042) and Pediococcus pentosaceus (KABP-041) included in HMF Baby Drops, demonstrated an increase in gut microbiome diversity, in addition to exhibiting a 69% reduction in crying time. The combination of probiotics in HMF Baby Drops has been found effective in helping benefit colic symptoms for both breastfed and formula-fed infants.