Clinical trials have found that horse chestnut extract can reduce pain and leg swelling associated with CVI and also significant reduction in symptoms, bleeding, and improvements in endoscopic evaluations in those with hemorrhoids. One trial showed that 82% of subjects had hemorrhoid improvements compared to only 32% in placebo, with most benefits acutely apparent within just six days of starting supplementation. Conversely, many studies for CVI find that maximum benefits occur within 1-3 months of supplementation. The evidence-based dose for Aesculus hippocastanum appears to be mostly dependent on escin content, which should reach a minimum 150mg per day, rather than the dried herb equivalent or total extract amount.

Horse Chestnut from Cyto-Matrix contains 375mg of Aesculus hippocastanum seed extract, standardized to contain a minimum of 20% escin content (75mg) per vegetable capsule. Horse Chestnut is also guaranteed to be free of esculin, a coumarin compound that can cause gastric distress in significant amounts. Each bottle of Horse Chestnut contains 90 vegetable capsules.

Horse Chestnut is a part of the Cyto-Matrix Herbal Matrix Series, containing sustainably sourced, traceable, and GMO free herbs with potent therapeutic properties. Each herb is extracted and tested to ensure the standardization of active ingredients, ultimately leading to efficacious, predictable and reliable products. The Cyto-Matrix Herbal Matrix Series of herbal extracts is beneficial for both the health of individuals, and also the health of our planet and future generations.