S-Adenosyl-L-Methionine (SAMe) is a natural compound and methyl group donor that supports the methylation cycle, a process which is essential for many aspects of health. Methylation is fundamental for ridding the body of certain toxins, and certain people, such as those with chronic liver disorders, cannot produce adequate levels of SAMe.

SAMe’s effectiveness to support a balanced mood is demonstrated by many clinical studies. SAMe is in fact so effective for boosting a low mood that it is legally registered as a prescription drug in several European countries for mood balance.  One study showed that SAMe was as effective as a common prescription medication for mood. It is thought that SAMe works by help boosting serotonin, dopamine and melatonin levels in the brain, low levels of which are commonly associated with mood imbalances such as anxiety and depression. SAMe has also been found to support joint health in osteoarthritis patients as effectively as a popular anti-inflammatory drug by reducing inflammation and protecting joint tissue from degradation.

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Adult DosageTake two or three tablets daily on an empty stomach, or as directed by a qualified health care practitioner. Use for a minimum of four weeks to see beneficial effects for osteoarthritic pain and a minimum of two weeks for mood support.CautionsDo not take it at night, since this product may cause anxiety, restlessness and insomnia. Consult a health care practitioner prior to use if you are pregnant or breastfeeding, suffer from depression or are taking medications that may influence serotonin levels (e.g. antidepressants).

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At Wellness Supplement, we strive to provide up-to-date product information and images on our website. However, please be aware that manufacturing changes to packaging or ingredients may occasionally occur before updates are reflected on our site.

Products may ship with different packaging due to recent updates from the manufacturer or supplier. In most cases, the ingredients remain the same despite the packaging change. However, we strongly recommend reading all labels, warnings, and directions before use. Please do not rely solely on the information provided on Wellness Supplement’s website.

Probiotics are shipped with a free ice pack. While the product may not be cold upon delivery, the ice pack helps maintain a cooler temperature during transit. Please consider weekend and holiday delays when placing an order. 

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